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Guayaquil to Santiago Flights — Fares from $275.00 | GYE–SCL

Compare the cheapest Guayaquil (GYE) to Santiago (SCL) fares found by our live flight search, then book online or over the phone with our travel experts.

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Adults
12+
1
Children
2–11
0
Infants
Under 2
0
Cabin
🏷️
Save up to 40% with unpublished phone fares
Consolidator deals on selected Guayaquil → Santiago flights that do not appear in online search results. The live fares below are bookable right now — or call to check for an unpublished fare on your dates.
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One-way fares Guayaquil → Santiago

showing indicative fares · loading live prices…
LATAM
LATAM CHEAPEST
GYE → SCL · Economy
lowest fare seen on this route
$459.63
$275.78
Select
Copa Airlines
Copa Airlines
GYE → SCL · Economy
lowest fare seen on this route
$859.69
$515.81
Select
See all flights & times → Prices per adult, one way, incl. taxes & fees. Availability changes constantly.
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Live fares we can book on GYE–SCL

Lowest fare found per airline on the GYE → SCL route, with our discounted phone-deal price.

AirlineCabin Found fareOur discounted fare Fare found on
LATAM LATAM Economy $459.63 $275.78 Aug 14, 2026 Book
Copa Airlines Copa Airlines Economy $859.69 $515.81 Aug 14, 2026 Book

Discounted fares are negotiated phone deals from our vendor network and may not appear in online search results — call 765-995-0868 to lock one in. Fares were found on the dates shown, are per person in USD, and change with availability.

More routes we cover

Guayaquil to New York Guayaquil to Orlando Guayaquil to Puerto Montt Ciudad de la Costa to Santiago Punta Cana to Santiago All routes →

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FlyLemo is an independent travel agency — call 765-995-0868 or use the search above to compare live fares on this route. See our terms, privacy policy, refund policy and service fees for full details, or contact us any time.

Page updated August 16, 2026 · fare data refreshed automatically from live flight searches.